La relación entre el consumo de determinados colorantes alimentarios artificiales presentes en postres, refrescos o biscochos o galletería industrial y comportamientos hiperactivos y de déficit de atención en niños, es una cuestión no resuelta que periódicamente reaparece en el debate científico.
Esta controversia ha vuelto a la actualidad después de que el miércoles se hiciera público que la agencia estadounidense del medicamento (FDA) haya decidido revisar los estudios existentes y se plantee obligar a incluir advertencias en los envases de alimentos que usen estas sustancias.
La Agencia Europea de Seguridad Alimentaria (AESA) hacía algún tiempo que ya había tomado la delantera. La Comisión aprobó el año pasado un programa para reevaluar los aditivos alimentarios antes de 2009, y se dio prioridad a los colorantes.
Mientras, sectores de la medicina cuestionan estos vínculos y defienden las fuertes raíces genéticas del trastorno de la hiperactividad y el déficit de atención.
"No existe ninguna evidencia científica sobre la relación entre el consumo de estos productos y la hiperactividad", sostiene Fernando Muelas, jefe de servicio de Neuropediatría del hospital La Fe de Valencia. 'Es un tema muy revisado y no hay datos concluyentes'.
Este especialista destaca que se han descubierto "cinco genes cuyas alteraciones están ligadas a este trastorno, que tiene un origen genético en un 80% de los casos", agrega.
Y señala que "en el 20% restante tiene que ver con comportamientos de riesgo en el embarazo, como el consumo de alcohol y tabaco".
La FDA, en el equilibrio que mantiene entre los sectores del activismo ambiental y los intereses de la industria alimentaria, defendió los últimos años la inocuidad de los colorantes artificiales hasta que, recientemente, se replanteó su postura.
El diario "The New York Times" informó que esta entidad ha encargado a un panel de expertos la revisión de los estudios existentes sobre los efectos en el comportamiento de estos aditivos en determinados niños con trastornos de conducta a quienes el consumo de los colorantes podría agudizar su problema.
Entre las medidas que se plantean está la posibilidad de que las golosinas, bebidas, cereales infantiles y demás productos que usan estas sustancias en su elaboración incluyan en el envase mensajes que adviertan de la posibilidad de que su consumo puede empeorar el comportamiento de niños hiperactivos.
A raíz de un estudio publicado en The Lancet en 2007, la autoridad alimentaria europea -adelantándose a la revisión general acordada en 2009- examinó los umbrales de seguridad del consumo diario del amarillo de quinoleína (E104), amarillo anaranjado (E110) y rojo cochinilla 4R (E124). También de la tartrazina (E102), azorrubina/carmoisina (E122) y rojo allura AC (E129).
El artículo de la revista médica británica indicaba que el consumo de estas seis sustancias o sus combinaciones (frecuentes en productos de confitería, postres, panadería o refrescos) podría haber sido la causa del aumento de la hiperactividad en los niños estudiados.
La AESA solo detectó que la tartrazina podía causar reacciones de intolerancia, como irritaciones cutáneas, y en un pequeño porcentaje de población. La agencia europea continúa en su examen a los aditivos.
After staunchly defending the safety of artificial food colorings, the federal government is for the first time publicly reassessing whether foods like Jell-O, Lucky Charms cereal and Minute Maid Lemonade should carry warnings that the bright artificial colorings in them worsen behavior problems like hyperactivity in some children.
The Food and Drug Administration concluded long ago that there was no definitive link between the colorings and behavior or health problems, and the agency is unlikely to change its mind any time soon.
But on Wednesday and Thursday, the F.D.A. will ask a panel of experts to review the evidence and advise on possible policy changes, which could include warning labels on food.
The hearings signal that the growing list of studies suggesting a link between artificial colorings and behavioral changes in children has at least gotten regulators’ attention — and, for consumer advocates, that in itself is a victory.
In a concluding report, staff scientists from the F.D.A. wrote that while typical children might be unaffected by the dyes, those with behavioral disorders might have their conditions “exacerbated by exposure to a number of substances in food, including, but not limited to, synthetic color additives.”
Renee Shutters, a mother of two from Jamestown, N.Y., said in a telephone interview on Tuesday that two years ago, her son Trenton, then 5, was having serious behavioral problems at school until she eliminated artificial food colorings from his diet.
“I know for sure I found the root cause of this one because you can turn it on and off like a switch,” Ms. Shutters said.
But Dr. Lawrence Diller, a behavioral pediatrician in Walnut Creek, Calif., said evidence that diet plays a significant role in most childhood behavioral disorders was minimal to nonexistent. “These are urban legends that won’t die,” Dr. Diller said.
There is no debate about the safety of natural food colorings, and manufacturers have long defended the safety of artificial ones as well. In a statement, the Grocery Manufacturers Association said,
“All of the major safety bodies globally have reviewed the available science and have determined that there is no demonstrable link between artificial food colors and hyperactivity among children.”
In a 2008 petition filed with federal food regulators, the Center for Science in the Public Interest, a consumer advocacy group, argued that some parents of susceptible children do not know that their children are at risk and so “the appropriate public health approach is to remove those dangerous and unnecessary substances from the food supply.”
The federal government has been cracking down on artificial food dyes for more than a century in part because some early ones were not only toxic but were also sometimes used to mask filth or rot.
In 1950, many children became ill after eating Halloween candy containing Orange No. 1 dye, and the F.D.A. banned it after more rigorous testing suggested that it was toxic. In 1976, the agency banned Red No. 2 because it was suspected to be carcinogenic. It was then replaced by Red No. 40.
Many of the artificial colorings used today were approved by the F.D.A. in 1931, including Blue No. 1, Yellow No. 5 and Red No. 3. Artificial dyes were developed — just as aspirin was — from coal tar, but are now made from petroleum products.
In the 1970s, Dr. Benjamin Feingold, a pediatric allergist from California, had success treating the symptoms of hyperactivity in some children by prescribing a diet that, among other things, eliminated artificial colorings.
And some studies, including one published in The Lancet medical journal in 2007, have found that artificial colorings might lead to behavioral changes even in typical children.
The consumer science group asked the government to ban the dyes, or at least require manufacturers to include prominent warnings that “artificial colorings in this food cause hyperactivity and behavioral problems in some children.”
Citizen petitions are routinely dismissed by the F.D.A. without much comment. Not this time.
Still, the agency is not asking the experts to consider a ban during their two-day meeting, and agency scientists in lengthy analyses expressed skepticism about the scientific merits of the Lancet study and others suggesting any definitive link between dyes and behavioral issues.
Importantly, the research offers almost no clue about the relative risks of individual dyes, making specific regulatory actions against, say, Green No. 3 or Yellow No. 6 almost impossible.
The F.D.A. scientists suggested that problems associated with artificial coloring might be akin to a peanut allergy, or “a unique intolerance to these substances and not to any inherent neurotoxic properties” of the dyes themselves.
As it does for peanuts and other foods that can cause reactions, the F.D.A. already requires manufacturers to disclose on food labels the presence of artificial colorings.
A spokeswoman for General Mills refused to comment. Valerie Moens, a spokeswoman for Kraft Foods Inc., wrote in an e-mail that all of the food colors the company used were approved and clearly labeled, but that the company was expanding its “portfolio to include products without added colors,” like Kool-Aid Invisible, Capri Sun juices and Kraft Macaroni and Cheese Organic White Cheddar.
The panel will almost certainly ask that more research on the subject be conducted, but such calls are routinely ignored. Research on pediatric behaviors can be difficult and expensive to conduct since it often involves regular and subjective assessments of children by parents and teachers who should be kept in the dark about the specifics of the test. And since the patents on the dyes expired long ago, manufacturers have little incentive to finance such research themselves.
Popular foods that have artificial dyes include Cheetos snacks, Froot Loops cereal, Pop-Tarts and Hostess Twinkies, according to an extensive listing in the consumer advocacy group’s petition. Some grocery chains, including Whole Foods Market and Trader Joe’s, refuse to sell foods with artificial coloring.
Fuente: The New York Times.
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